If you are willing to allow some changes in the formatting, you may as well just pipe it through cat
ls | cat
No colours, but newline for each entry.
Edit:
Turning off colors via the shell settings
Check your shell's rc file(s) and see where colors are set, then make a new .<shell>rc_mono where these settings are removed, source it and done. E.g. for bash:
$cat ~/.bashrc_mono
export TERM=xterm-mono
. ~/.bashrc
alias ls='ls --color=none'
alias grep='grep --color=none'
Note that . ~/.bashrc must precede the new aliases for ls and grep as their coloring usually is set in ~/.bashrc.
So all you need to do is
. ~/bashrc_mono ; ls
Accordingly a "redo colors"-rc might be nice:
$cat ~/.bashrc_recolorize
export TERM=xterm-256color
. ~/.bashrc
Use e.g. htop and you will see the difference.