Perl allows this with its syscall function:
$ perldoc -f syscall
syscall NUMBER, LIST
Calls the system call specified as the first element of the list,
passing the remaining elements as arguments to the system call. If
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The documentation also gives an example of calling write(2):
require 'syscall.ph'; # may need to run h2ph
my $s = "hi there\n";
syscall(SYS_write(), fileno(STDOUT), $s, length $s);
Can't say I've ever used this feature, though. Well, before just now to confirm the example does indeed work.
This appears to work with getrandom:
$ perl -E 'require "syscall.ph"; $v = " "x8; syscall(SYS_getrandom(), $v, length $v, 0); print $v' | xxd
00000000: 5790 8a6d 714f 8dbe W..mqO..
And if you don't have getrandom in your syscall.ph, then you could use the number instead. It's 318 on my Debian testing (amd64) box. Beware that Linux syscall numbers are architecture-specific.