I can't disable natural scrolling. That is, no matter whether I turn "Natural Scrolling" on or off, dragging the mouse wheel towards me scrolls up.
$ gnome-shell --version
GNOME Shell 3.20.4
$ cat /etc/redhat-release
Fedora release 24 (Twenty Four)
No matter what I set it to, if I go back to all settings and then open the "Mouse & Touchpad" settings again, the on/off state is persisted. So it seems whatever state that is setting is not used by the mouse driver.
